ANGELES ECOSYSTEM

SYNTHETIC IMMUNE RECEPTOR-T (SIR-T) PLATFORM

A next generation CAR-T platform that provides physiological T cell signaling.

SYNTHETIC ANTIGEN RECETPOR NK PLATFORM

A next generation NK-CAR platform

BISPECIFIC AND MULTISPECIFIC PLATFORMS

Bispecific and multi-specific SIR-T and NK-CAR platforms

UNIVERSAL PLATFORMS

Universal SIR and NK-CAR platforms

IN VIVO Platform

An in vivo platform for engineering next generation cell therapies

ALLOGENEIC PLATFORMS

Angeles platforms are fully compatible with allogeneic use

CAR-T TOXICITY MODULATORS

Use of Dasatinib to control CRS and other complications associated with cell therapies

CO-STIMULATION PLATFORM

A novel platform for providing selective NF-kappa B co-stimulus to CAR-T, TCR-T and other cell therapy products

Stem-Like T cell isolation Platform

A novel platform for isolation of T stem cells for generation of cell therapy products

MATADOR CYTOTOXICITY ASSAYS

Novel luciferase based non-radioactive cellular cytotoxicity assays

TOPANGA ASSAY

A novel luciferase based assay to measure expression and affinity of cell therapy products

MALIBU-GLO ASSAY

A novel luciferase based assay for antibody engineering